Scientific journal

60 2021

Journal of Food and Nutrition Research
Summary No. 2 / 2021

Omeragic, E. – Radosevic, D. – Causevic, A. – Marjanovic, A. – Djedjibegovic, J. – Sober, M.
Exposure assessment and risk characterization of metals intake through consumption of wine by population of winemakers in Bosnia and Herzegovina and Croatia
Journal of Food and Nutrition Research, 60, 2021, No. 2, s. 111-123

Elma Omeragic, Department of Pharmaceutical Analysis, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina. E-mail:

Received 20 November 2020; 1st revised 12 March 2021; accepted 13 April 2021; published online 23 May 2021.

Summary: The primary focus of this study was to determine the amounts of arsenic, iron, lead, cadmium, nickel and copper in wines originating from Bosnia and Hercegovina and Croatia, and to estimate the toxicological risk associated with the consumption of wine regarding selected heavy metals. The metals content was determined in 57 wine samples. Analysis of the metals was performed by graphite furnace atomic absorption spectrometry. The wine consumption levels as well as body mass values were determined using questionnaires specially designed for the purposes of this study and conducted among winemakers (n = 46). The health risk was determined by the estimated daily intake, hazard index (HI) and cancer risk (Rc). To estimate the daily intake of selected metals through wine consumption, 36 different scenarios using a 4 × 3 × 3 design were developed. For each of these scenarios, HI and Rc were calculated. The content of metals was below the maximum residue level set by the European Union and also by Bosnia and Herzegovina. Cd content was generally higher in wine samples originating from the Dalmatia region in Croatia. HI and Rc for certain scenarios of exposition showed possible health risks that were unacceptable.

Keywords: wine; heavy metal; atomic absorption spectrometry; health risk

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