Výskumný ústav potravinársky

Park, E. – Kwon, K. H.
Metabolic characteristics and health effects of low-calorie sweeteners focusing on the prevention of obesity and metabolic diseases
Journal of Food and Nutrition Research, 64, 2025, č. 2, s. 104-114

Ki Han Kwon, College of General Education, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, 02707 Seoul, South Korea. e-mail: kihan.kwon@kookmin.ac.kr

Review article
Received 22 April 2025; 1st revised 25 May, 2025; accepted 25 June 2025; published online 2 July 2025.

Súhrn: Low-calorie sweeteners (LCSs) are attracting attention as sugar substitutes, and many studies are being conducted, especially in relation to the prevention of obesity and metabolic diseases. These sweeteners are characterised by low calories and blood sugar index (GI), and may play a role in minimising insulin response and suppressing weight gain. In this review paper, the chemical structure and metabolic characteristics of representative LCSs (allulose, erythritol, stevia, etc.) were analysed, and their effects on health were comprehensively considered. In particular, the efficacy and limitations of LCSs were compared, focusing on their association with obesity, type 2 diabetes and cardiovascular disease. In addition, the recently researched physiological mechanisms of sweeteners and their interactions with microbiomes were discussed. Finally, by evaluating the regulatory status and industrial application potential of each country, the directions for continuous research and application of LCSs were presented. The purpose of this study is to provide a scientific basis for healthy sweetener choices for the prevention of metabolic diseases.

Kľúčové slová: low-calorie sweeteners; allulose; metabolic health; obesity; blood sugar control

Na stiahnutie:
  jfnr-2025-2-pp104-114-park.pdf (PDF, 372.86 Kb, 221x)