Vedecký časopis

51 2012

Journal of Food and Nutrition Research
Súhrny čísla 2 / 2012

Mošovská, S. – Bírošová, L. – Valík, Ľ.
The impact of pseudocereal extracts with antioxidant and antimutagenic activity on development of antibiotic resistance
Journal of Food and Nutrition Research, 51, 2012, č. 2, s. 102-108

Silvia Mošovská, Department of Nutrition and Food Assessment, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia. Tel.: +421259325761, e-mail: silvia.mosovska@stuba.sk

Súhrn: This research investigates the ability of extracts from amaranth, buckwheat, Japanese millet and sorghum to influence the development of antibiotic resistance in the antibiotic-sensitive bacteria. Effects on ciprofloxacin resistance were studied in Salmonella Typhimurium. In case of Staphylococccus aureus, the study aimed at ampicillin resistance. Sorghum extract decreased the frequency of spontaneous mutations leading to both ciprofloxacin and ampicillin resistance. This extract also lowered the mutation frequency induced by 3-(5-nitro-2-furyl)acrylic acid leading to ciprofloxacin resistance. Extract from amaranth suppressed the frequency of spontaneous mutations, but increased the mutation frequency induced by 2-nitrofluoren leading to ampicillin resistance. Japanese millet, buckwheat and amaranth extracts raised the frequency of spontaneous mutations leading to ciprofloxacin resistance. Buckwheat extract displayed no effect on mutation frequency leading to ampicillin resistance. The antioxidant activity of pseudocreal extracts was also determined.

Kľúčové slová: pseudocereals; antibiotic resistance; ampicillin; ciprofloxacin; antioxidants

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